Antwerp take on Tottenham at Bosuilstadion in Group J of the UEFA Europa League. Spurs have managed just one win from their last eight Europa League away games.
Lille host Celtic in Group H of the UEFA Europa League at Stade Pierre-Mauroy. Lille's Yusuf Yazici netted a hat-trick against Sparta Prague on matchday one.
Leicester City travel to the Athens Olympic Stadium to take on AEK Athens in Group G of the UEFA Europa League. Leicester prevailed 3-0 winners over Zorya on matchday one.
Arsenal host Dundalk at the Emirates Stadium in Group B of the UEFA Europa League. This is the first time that Arsenal will face Irish opposition in UEFA competition.
Rangers host Lech Poznan at Ibrox Stadium in Group D of the UEFA Europa League. Rangers striker Kemar Roofe scored the longest-range goal in UEFA Europa history on matchday one.
Coventry City welcome Reading to St Andrew's for a Friday evening clash from the Sky Bet Championship.